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The study sample was further restricted to adults who reported having MCCs (i.e., two or more chronic physical conditions or having a combination of chronic physical and mental health conditions).

MCCs were defined from the following list of chronic physical and mental health conditions: asthma, arthritis, cancer, chronic obstructive pulmonary disease (COPD), diabetes, heart diseases, hyperlipidemia, hypertension, bipolar disorder, depression, or other mental health disorders.

In adults with and without chronic conditions, sex differences in CAM use exist [5–10].Model I examined the unadjusted association between sex and CAM use (i.e., without controlling for any other independent variables).Model II controlled for demographic characteristics (age, race/ethnicity, and the region of residence).Multivariable regression analyses were used to examine the association between sex and CAM use. A significantly higher percentage of women compared to men had ever used CAM (51.5% versus 44.3%); women were more likely to have ever used CAM (AOR = 1.49, 95% CI = 1.35–1.65).Among CAM users, a higher percentage of women compared to men used CAM in the past 12 months (53.5% vs.Identifying the factors that influence the CAM use among men and women with MCCs is important because of the high and increasing prevalence of MCCs in the United States (US), specifically among women.

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