(6) The flow of sodium ions across the membrane into the muscle cell generates an action potential which induces muscle contraction.
Skeletal muscles are directly controlled by motor neurons located in the spinal cord or, in a few cases, the brainstem.
They are named for chemicals that can selectively activate each type of receptor without activating the other: muscarine is a compound found in the mushroom Amanita muscaria; nicotine is found in tobacco.
Nicotinic acetylcholine receptors are ligand-gated ion channels permeable to sodium, potassium, and calcium ions.
Parts in the body that use or are affected by acetylcholine are referred to as cholinergic.
Substances that interfere with acetylcholine activity are called anticholinergics.